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Understanding Breast Cancer Genetics

Barbara T. Zimmerman, PhD

 

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This concise book for general readers explains the genetic bases of the disease that strikes one in eight women in the United States and kills more than 40,000 annually. Although they are more likely to die of heart disease or lung cancer, women are in greater fear of breast cancer.

Understanding Breast Cancer Genetics explains the genetic bases of both sporadic and inherited breast cancers. Although only 5%-10% of breast cancer patients develop an inherited form of the disease, all women need to understand the role of genes in the sporadic forms of the disease.

Dr. Zimmerman examines the general biology of breast cancer, describing how sporadic and inherited forms arise and how the location of the tumors affect the body. She discusses mutations and their role in the development of tumors and relates the history of our understanding of the interaction of genes, environment, and cancer.

Covered too are the issues of risk, prevention, screening, diagnosis, therapy, genetic testing, and counseling. Dr. Zimmerman concludes with a comprehensive analysis of current research and with an emphasis on how a woman's understanding of inherited breast cancer can help doctors seeking to design better methods for prevention and therapy. A useful list of resources for further information about the genetics of breast cancer is included.

Barbara T. Zimmerman earned her doctorate in experimental pathology and did post-doctoral research in the cellular and molecular processes of disease. Widely published, she is the manager of the Denver-based firm, Biomedical Communication and Consulting.

128 pages

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Breast Cancer Genetics